Partnering Projects

The partnering mechanism allowed a funded project to add new knowledge, competencies, ideas and resources to the HBP Flagship, and to benefit from the Research Infrastructure and the other capabilities made available by the HBP.

Partnering Projects were important to create synergies between the Human Brain Project and the activities receiving funding at regional, national or transnational level. Openness was key to the ability of the HBP to remain at the cutting edge of scientific, technological and innovation developments.

Partnering Projects allowed the EBRAINS Research Infrastructure (RI) to engage stakeholders with a formal and facilitated management process in which all Project stakeholders voluntarily agree to adopt a cooperative, team-based approach to observe successful project outcomes and contribute to the EBRAINS’ mission: to continue serving the scientific and academic community in further boosting research in brain science, combining neuroscience with modern ICT, and translate that knowledge into medical and technological progress, and concrete implementation output, benefiting patients and society. These formal processes are envisaged to foster longer-term and closer relationships with the stakeholders, which could potentially contribute to the construction and consolidation of the RI.

What was a Partnering Project? 

Partnering Projects (PPs) and their partners, who become for many of them Associated Members (AMs) were part of the Flagship. Many contributed to the implementation of the HBP research roadmap by performing research, innovation and networking activities of mutual interest in cooperation with HBP Core Project members. *This included:

  • Performing research that added novel capabilities to the RI; 
  • Performing research that used the RI to address previously intractable issues in neuroscience; 
  • Developing novel computing and robotics technologies and applications; 
  • Improving the understanding, diagnosis and treatment of brain disorders; 
  • Using the RI to innovate in any field profiting from technology and tools developed by the HBP Core Project's members.

* Human Brain Project Partnering Projects Meeting: Status Quo and Outlook, eNeuro, 2023 Sep, Vezoli et al. DOI:

Partnering Projects representatives 

The Partnering Project representatives represented the interest of the Partnering Environment, including Partnering Projects and Associated Members, in the Scientific and Infrastructure Board of the HBP. They fostered collaborations between the Partnering Environment and the HBP Core Project.

Associate Members 

Associated Members can be found here

Partnering Projects

During the HBP, HBP formalized 76 Partnering Projects (PPs). These projects were funded by different sources (10 % by EU funding, 22 % by national funding, 27% by the Joint Transnational Calls of FLAG-ERA and 41 % from EBRAINS RI Voucher Programme). Notably, 48 coordinators’ institutions were not HBP members. 

The PPs’ coordinators institutions were mostly from the European Union (n=53) but also from institutions in the United States of America (n=5), UK (n=10), Canada (n=3), Australia (n=2), India (n=1) and Japan (n=2).


TraP-MEDD (22/12/2022 -31/03/2023)
Translational Platform for MSA: Elucidation of Disease-mechanisms and Drug discovery

ParkinsonBrain (2022/01/01 - 2022/12/31)
Prediction of neurosurgical treatment outcomes in Parkinson’s disease

TVB-CD (1/4/2018 - 31/3/2024) 
Building a Personalized Virtual Brain with Neurodegenerative Disease to Guide Clinical Decisions 

HIBALL (1/4/2020 - 31/3/2023) 
Helmholtz International BigBrain Analytics and Learning Laboratory 

Macaque vision (1/9/2019 - 31/3/2023) 
Biomimetic modeling of macaque visual cortex 

HA-CTion (1/3/2020 - 28/2/2023)
Hypothalamic histaminergic modulation of brain regions involved in fear memory 

SMART BRAIN (1/1/2020 - 31/12/2022) 
Advanced Morphological Reconstruction of Human Brain Tissue by Multimodal Fusion of Multiscale Optical Imaging Technologies 

TVB-CLOUD (1/12/2018 - 30/11/2022) 

MILEDI (1/12/2019 - 30/11/2022) 
Multiscale Modelling of Impaired LEarning in Alzheimer’s Disease and Innovative Treatments 

HPN-H&D (1/9/2017 - 30/9/2022) 
Human Projection Neurons in Health & Disease 

AI-Mind (7/7/2021 - 31/3/2023) 
Intelligent digital tools for screening of brain connectivity and dementia risk estimation in people affected by mild cognitive impairment 

EpiCARE (1/3/2017 - 28/2/2022) 
European Reference Network for rare and complex epilepsies 

RGS@HOME (1/1/2019 - 31/12/2021) 
The RGS@home project: Scaling ICT based neurorehabilitation to personalized 24/7 home care 

EpiSensor (28/3/2019 - 27/3/2021) 
Wearable Sensors and Epilepsy 

Brainsynch-Hit (1/1/2018 - 30/11/2020) 
Alterations of functional connectivity in the human brain after focal lesion and cognitive function: empirical and modeling studies 

ADNeuronModel (1/6/2019 - 31/3/2020) 
Modeling neuron dysfunction in Alzheimer’s disease 

CREACTIVE (1/10/2013 - 31/3/2020) 
Collaborative REsearch on ACute Traumatic brain Injury in intensiVE care medicine in Europe 

IHAVTVB (1/7/2019 - 31/3/2020) 
Interaction between Human Atlas Viewer and The Virtual Brain 


VIPattract (17/05/2022 – 31/03/2023)
The role of GABAergic neuronsubtypes in stabilizing and flexiblyresetting head-direction signals in thePresubicular cortex

ModelDXConsciousness (17/03/2022 -31/03/2023)
Combining model free and model-based biomarkers for the consciousness diagnosis

MULTIVIsion (09.12.2022-31.01.2023)
Multiphoton Voltage Imaging

4D-EEG (-31.3.2023)
4D-EEG: From brain signal propagation to functional understanding

DoCMA (31.08.2022 - 31.01.2023)
Disorders of Consciousness: enhancing the transfer of knowledge and professional skills on evidence-based interventions and validated technology for a better management of patients

BBM-CREF (18/8/2022 - 31/3/2023)
Brain Biophysical Models

NeuronsReunited (1/1/2020 - 31/12/2023) 
Neurons reunited: data and software to reconstruct long-range projection neurons from brain tissue, place them in a digital reference brain with high precision, and model their interactions 

NeuroSMS (1/7/2021 - 31/3/2023) 
Simulating direct calcineurin suppression of protein kinase A in neurons 

CORTICITY (1/12/2017 - 31/3/2023) 
Comparative Investigation of the Cortical Circuits in Mouse, NHP and Human 

ATLAS-cer (1/4/2020 - 31/3/2023)
Enhanced mouse atlas for cerebellar connectivity 

Subschiz (21/6/2021 - 21/3/2023) 
Startle-network modelling for schizophrenia research – insights from subcellular models of neuromodulation 

BUILD (1/1/2020 - 21/3/2023) 
Big mUltimodal hIgh-resolution atLas Data Management 

SENSEI (1/3/2020 - 28/2/2023) 
SEgmentation of Neurons using Standard and supErresolution 

PrimCorNet (1/2/2020 - 31/1/2023) 
Layer-specific characterization and modeling of fronto-parietal dynamics in primate cortical networks 

SoundSight (1/1/2020 - 31/12/2022) 
The sight of sound: how vision shapes the development of auditory inputs to the occipital cortex 

MoDeM (1/12/2019 - 30/11/2022) 
The "Motor-way" to Decision Making: how the motor system drives cue-triggered decisions 

DOMINO (1/12/2019 - 31/03/2023) 
Development Of cortical Multisensory Integration mechanisms at micro- and macro-scales during NOrmal and pathophysiological conditions 

CerebNEST (1/6/2016 - 31/10/2022) 
Large-scale network models of the cerebellum for sensorimotor robotic control 

NextGen (1/9/2021 - 31/3/2023) 
Next generation neural mass models: bridging the scales from micro to macroscopic dynamics 

SHERPA (1/5/2018 - 30/11/2021) 
Shaping the ethical dimensions of information technologies – a European perspective 

BOLDsim (26/10/2020 - 26/10/2021) 
BOLD signal reconstruction and simulation from cellular data-driven models 

HippoTrisynPlasticity (1/6/2020 - 31/5/2021) 
Multiscale Hippocampal Models for Neuronal Plasticity: Integration to the Brain Simulation Platform 

EXABRAINPREP & RoBoBrain (1/4/2020 - 31/3/2021) 
Project 1: Preparing brain models for exascale systems 
Project 2: Whole-brain spiking neural network and rodent musculo-skeletal models integration for behavioral experimentation in the neurorobotics platform 

Async-Prop (3/3/2017 - 2/3/2021) 
Propagating Activity in Isolated Cortical Networks at the Edge of Asynchrony 

MAC-Brain (1/3/2018 - 1/3/2021) 
Developing a Multi-scale account of Attentional Control as the constraining interface between vision and action: A cross-species investigation of relevant neural circuits in the human and macaque Brain. 

MOSAIC (1/2/2019 - 28/2/2021) 
Modulation of slow OScillAtions In Cognitive tasks 

HIPPOPLAST (1/3/2018 - 28/2/2021) 
How rigid and plastic circuits contribute to hippocampal function 

SCALES (1/1/2018 - 31/1/2021) 
Studying Cognitive Activity at two Levels with Simultaneous depth and surface recordings 

InterneuronAxon (1/9/2016 - 31/8/2020) 
Axon signalling in hippocampal fast-spiking interneurons 

CHAMPMouse (1/12/2015 - 20/6/2020) 
CHArting Multi-areal Visual Perception in the Mouse 

HBP-SciUnit (15/5/2019 - 14/5/2020) 
Enhancing HBP Model Validation using SciUnit 

HippoPlasticity (1/4/2019 - 1/4/2020) 
Multiscale Hippocampal Models for Neuronal Plasticity: Integration to the Brain Simulation Platform 

MAPS (11/4/2019 - 30/4/2020) 
Mapping Brain Circuits in Spatial Navigation 

CANON (1/2/2016 - 31/3/2020) 
Investigating the canonical organization of neocortical circuits for sensory integration 

MULTI-LATERAL (15/6/2016 - 31/12/2019) 
Multi-level Integrative Analysis of Brain Lateralization for Language 

FUSIMICE (1/1/2016 - 30/11/2019) 
Ultrafast Functional Ultrasound (fUS) Imaging for Highly-Resolved Targeted Mapping of Functional Connectivity in the Awake Mouse Brain 

SloW-Dyn (1/12/2015 - 30/11/2018) 
Slow Wave Dynamics: from experiments, analysis and models to rhythm restoration


ReWoMeN (27.11.2022 - 31.3.2023)
Recall dynamics of working memory networks: Modeling, analysis, and applications

SaNeTouch (28/07/2022 – 31/03/2023)
Shared Autonomy Neuroprosthetics: Bridging the gap between Artificial and Biological Touch

CATRA (12/01/2022 - 31/03/2023)
Cognitive Architecture for Therapy Robots and Avatars

Async-Neuromorph (8/9/2021 - 31/3/2023)
Neuromorphic Hardware Operating at the Edge of Asynchrony

NESTSONATA (15/9/2021 - 31/3/2023)
Efficient support for Sonata in NEST

HART (11/11/2020 - 31/3/2023)
Human Augmentation Research & Technology

RobotBodySchema (1/1/2017 - 31/3/2023)
Robot self-calibration and safe physical human-robot interaction inspired by body representations in primate brains

EMBRACE (1/5/2021 - 31/10/2022)
EMBedding Responsible Research And Innovation in Future and Emerging TeChnologiEs

NEST Demoa (1/6/2021 - 31/5/2022)
NEST-demoa co-simulation: Towards linking closed-loop motor control models to multi-scale experimental data

StriatalPlas (1/4/2020 - 31/3/2022)
Multiscale Striatal Models for Neuronal Plasticity: Integration to the Brain Simulation Platform

AstroNeuronNets (8/9/2021 - 22/2/2022)
Astrocyte-neuron interactions in large-scale networks: Developing new astrocyte modules for NEST simulator

Brains On Board (1/12/2016 - 31/12/2021)
Brains on Board: Neuromorphic Control of Flying Robots

SpICENet (1/4/2019 - 31/3/2021)
Spinal Input Connectome: Extracting the Functional Network

BRAINSPACE (23/2/2020 - 31/3/2021)
Workflow optimization for brain-wide spatial analysis to identify regional and cell-type correlates of resilience to Alzheimer’s in the AD-BXD mouse population

DOPAMAP (1/3/2020 - 28/2/2021)
Map of dopamine receptor positive cell types in the developing and adult mouse brain

NeuroReact (1/7/2017 - 30/6/2020)
Neural real-time planning for reactive industrial robots

SoRoN (4/1/2018 - 31/3/2020)
Soft Robotics with the HBP Neurorobotics Platform (NRP)

SpinnCer (1/5/2019 - 31/3/2020)
Neuromorphic hardware simulations of cerebrocortical-cerebellar loop

NESTDesktop (1/4/2019 - 16/3/2020)
NEST Desktop

SHADOW HBP (15/5/2019 - 15/3/2020)
Integration of Shadow Dexterous Hand with the HBP Neurorobotics Platform

FIIND (1/1/2016 - 30/11/2019)
Ferret Interactive Integrated Neurodevelopment Atlas

MoCoTi (1/3/2015 - 1/3/2018)
Motor Control and Timing in the Cerebellum: Spatio-Temporal Integration in Complex Neuronal Networks

HBP Partnering Project News

HBP Education E-Library – recorded lectures of the EBRAINS workshop “HBP Partnering Projects Meeting: status quo and outlook”

HBP Partnering Projects meet at Nijmegen to discuss their scientific outcomes and the future of EBRAINS, Sept 14, 2022

EBRAINS workshop: HBP Partnering Projects Meeting: status quo and outlook (5-7 September 2022)

The Human Brain Project welcomes 5 new Partnering Projects, June 21, 2021

CerebNEST: Alice Geminiani was awarded the Massimo Grattarola award for the best PhD thesis in Italy in the field of neuroengineering and biotechnology. She is working with CerebNEST and HBP/SP6, 2019

Brains on Board: These Insect-Inspired Robots Don't Need GPS For Orientation, April 5, 2019

CerebNEST: New neuronal model with potential to tackle spinocerebellar ataxias disease, February 28, 2019

CANON: Strengthening collaboration to model cortical function, May 2, 2018

FUSIMICE: New ultrasound technique shows the brain of rodents in action, February 28, 2018

CHAMPMouse: Investigating circuitous networks of connections, January 31, 2018

MULTI-LATERAL: Brain images refute language domain theory from the 60s, January 4, 2018

CANON: The brain is still ‘connected’ during non-REM sleep, December1, 2017

MoCoTi: ‘Low cost android’ to study the brain, October 19, 2017

SloW Dyn: ‘Waves’ of neural activity give new clues about Alzheimer’s, September 8, 2017



Satoshi Oota - SoRoN - HBP Partnering Projects Interview

Conrado Bosman - CANON and DOMINO - HBP Partnering Projects Interview

Matej Hoffmann - RobotBodySchema - HBP Partnering Projects Interview

Petra Ritter - TVB-Cloud - HBP Partnering Projects Interview

Simo Vanni - Macaque Vision - HBP Partnering Projects Interview

Laurence Brooks - SHERPA - HBP Partnering Projects Interview

Last update: 2023.09.13